Assessment of Treatment Response by Total Tumor Volume and Global Apparent Diffusion Coefficient Using Diffusion-Weighted MRI in Patients with Metastatic Bone Disease: A Feasibility Study

We describe our semi-automatic segmentation of whole-body diffusion-weighted MRI (WBDWI) using a Markov random field (MRF) model to derive tumor total diffusion volume (tDV) and associated global apparent diffusion coefficient (gADC); and demonstrate the feasibility of using these indices for assess...

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Detalhes bibliográficos
Main Authors: Blackledge, Matthew D., Collins, David J., Tunariu, Nina, Orton, Matthew R., Padhani, Anwar R., Leach, Martin O., Koh, Dow-Mu
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3977851/
https://ncbi.nlm.nih.gov/pubmed/24710083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0091779
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