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LRIG1 as a Potential Novel Marker for Neoplastic Transformation in Ocular Surface Squamous Neoplasia

The leucine rich repeats and immunoglobulin-like protein 1 (LRIG1) is a newly discovered negative regulator of epidermal growth factor receptor (EGFR) and a proposed tumor suppressor. It is not universally downregulated in human cancers, and its role in neoplastic transformation and tumorigenesis is...

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Hlavní autoři: Nagata, Maho, Nakamura, Takahiro, Sotozono, Chie, Inatomi, Tsutomu, Yokoi, Norihiko, Kinoshita, Shigeru
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3977825/
https://ncbi.nlm.nih.gov/pubmed/24709893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0093164
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