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Quantum mechanical study of solvent effects in a prototype S(N)2 reaction in solution: Cl(−) attack on CH(3)Cl

The nucleophilic attack of a chloride ion on methyl chloride is an important prototype S(N)2 reaction in organic chemistry that is known to be sensitive to the effects of the surrounding solvent. Herein, we develop a highly accurate Specific Reaction Parameter (SRP) model based on the Austin Model 1...

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Detalhes bibliográficos
Main Authors: Kuechler, Erich R., York, Darrin M.
Formato: Artigo
Idioma:Inglês
Publicado em: AIP Publishing LLC 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3977776/
https://ncbi.nlm.nih.gov/pubmed/24511924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.4863344
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