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A Phase I Study of Hepatic Arterial Infusion of Nab-Paclitaxel in Combination with Intravenous Gemcitabine and Bevacizumab for Patients with Advanced Cancers and Predominant Liver Metastases

PURPOSE: We conducted a Phase I clinical trial for patients with advanced cancer and predominant liver disease. EXPERIMENTAL DESIGN: Patients were treated with HAI nab-paclitaxel (120-210 mg/m(2); day 1); intravenous bevacizumab (10 mg/kg; day 1); and intravenous gemcitabine (600-800 mg/m(2); days 1...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Tsimberidou, Apostolia M., Ye, Yang, Wheler, Jennifer, Naing, Aung, Hong, David, Nwosu, Uchechi, Hess, Kenneth R., Wolff, Robert A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3977741/
https://ncbi.nlm.nih.gov/pubmed/23377373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-013-2088-y
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