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Murine interferon-beta receptor-mediated endocytosis and nuclear membrane binding.

Radioiodinated mouse interferon-beta (125I-MuIFN-beta) bound with high affinity (Kd = 9.8 X 10(-10) M) to plasma membrane of L929 murine fibroblasts (4-6 X 10(3) receptor sites per cell). The binding was saturable and inhibited by a 100-fold excess of unlabeled MuIFN-beta but not by excess mouse IFN...

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Detalhes bibliográficos
Main Authors: Kushnaryov, V M, MacDonald, H S, Sedmak, J J, Grossberg, S E
Formato: Artigo
Idioma:Inglês
Publicado em: 1985
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC397759/
https://ncbi.nlm.nih.gov/pubmed/3159015
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