Cyanide Toxicokinetics: The Behavior of Cyanide, Thiocyanate and 2-Amino-2-Thiazoline-4-Carboxylic Acid in Multiple Animal Models

Cyanide causes toxic effects by inhibiting cytochrome c oxidase, resulting in cellular hypoxia and cytotoxic anoxia, and can eventually lead to death. Cyanide exposure can be verified by direct analysis of cyanide concentrations or analyzing its metabolites, including thiocyanate (SCN(−)) and 2-amin...

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Bibliographic Details
Main Authors: Bhandari, Raj K., Oda, Robert P., Petrikovics, Ilona, Thompson, David E., Brenner, Matthew, Mahon, Sari B., Bebarta, Vikhyat S., Rockwood, Gary A., Logue, Brian A.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3977587/
https://ncbi.nlm.nih.gov/pubmed/24711295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jat/bku020
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