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Amphipathic Polymers Enable the Study of Functional Membrane Proteins in the Gas Phase

[Image: see text] Membrane proteins are notoriously challenging to analyze using mass spectrometry (MS) because of their insolubility in aqueous solution. Current MS methods for studying intact membrane proteins involve solubilization in detergent. However, detergents can destabilize proteins, leadi...

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Detalhes bibliográficos
Main Authors: Leney, Aneika C., McMorran, Lindsay M., Radford, Sheena E., Ashcroft, Alison E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2012
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3977578/
https://ncbi.nlm.nih.gov/pubmed/23072351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac302223s
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