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Complex RNA Folding Kinetics Revealed by Single-Molecule FRET and Hidden Markov Models
[Image: see text] We have developed a hidden Markov model and optimization procedure for photon-based single-molecule FRET data, which takes into account the trace-dependent background intensities. This analysis technique reveals an unprecedented amount of detail in the folding kinetics of the Diels...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Chemical
Society
2014
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3977575/ https://ncbi.nlm.nih.gov/pubmed/24568646 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja4098719 |
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