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Precision medicine and personalized breast cancer: combination pertuzumab therapy
Trastuzumab (Herceptin), a monoclonal antibody directed against the human epidermal growth-factor receptor 2 (HER2), is the poster child for antibody-based targeted therapy in breast cancer. Pertuzumab, another humanized monoclonal antibody, binds to a different domain of HER2 and prevents the forma...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Dove Medical Press
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3977457/ https://ncbi.nlm.nih.gov/pubmed/24715764 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/PGPM.S37100 |
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