RIG-I Detects mRNA of Intracellular Salmonella enterica Serovar Typhimurium during Bacterial Infection

The cytoplasmic helicase RIG-I is an established sensor for viral 5′-triphosphorylated RNA species. Recently, RIG-I was also implicated in the detection of intracellular bacteria. However, little is known about the host cell specificity of this process and the bacterial pathogen-associated molecular...

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Bibliographische Detailangaben
Hauptverfasser: Schmolke, Mirco, Patel, Jenish R., de Castro, Elisa, Sánchez-Aparicio, Maria T., Uccellini, Melissa B., Miller, Jennifer C., Manicassamy, Balaji, Satoh, Takashi, Kawai, Taro, Akira, Shizuo, Merad, Miriam, García-Sastre, Adolfo
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Microbiology 2014
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3977358/
https://ncbi.nlm.nih.gov/pubmed/24692634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01006-14
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