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Mechanism of activation of the heme-stabilized translational inhibitor of reticulocyte lysates by calcium ions and phospholipid.

We have reported previously that calcium ions and phospholipid activate the heme-stabilized proinhibitor form (pro-HCI) of the heme-controlled translational inhibitor (HCI) in reticulocyte lysates and promote the first step of the reaction pro-HCI in equilibrium reversible HCI----irreversible HCI. T...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: de Herreros, A G, de Haro, C, Ochoa, S
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1985
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC397726/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3159012/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.10.3119
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