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Tumor-promoting role of TGFβ1 signaling in ultraviolet B-induced skin carcinogenesis is associated with cutaneous inflammation and lymph node migration of dermal dendritic cells

Transforming growth factor beta 1 (TGFβ1) is a pleiotropic cytokine in the skin that can function both as a tumor promoter and suppressor in chemically induced skin carcinogenesis, but the function in ultraviolet B (UVB) carcinogenesis is not well understood. Treatment of SKH1 hairless mice with the...

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Detalhes bibliográficos
Main Authors: Ravindran, Anand, Mohammed, Javed, Gunderson, Andrew J., Cui, Xiao, Glick, Adam B.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3977148/
https://ncbi.nlm.nih.gov/pubmed/24363069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgt486
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