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Contribution of endogenous glucocorticoids and their intra-vascular metabolism by 11β-HSDs to post-angioplasty neointimal proliferation in mice

Exogenous glucocorticoids inhibit neointimal proliferation in animals. We aime to test the hypothesis that endogenous glucocorticoids influence neointimal proliferation; this may be mediated by effects on systemic risk factors or locally in vessels, and modulated either by adrenal secretion or by en...

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Detalhes bibliográficos
Main Authors: Iqbal, Javaid, Macdonald, Linsay J, Low, Lucinda, Seckl, Jonathan R., Yau, Christopher W, Walker, Brian R, Hadoke, Patrick WF
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3977041/
https://ncbi.nlm.nih.gov/pubmed/23125311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2012-1481
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