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Ligand Concentration Regulates the Pathways of Coupled Protein Folding and Binding
Coupled ligand binding and conformational change plays a central role in biological regulation. Ligands often regulate protein function by modulating conformational dynamics, yet the order in which binding and conformational change occurs are often hotly debated. Here we show that the “conformationa...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3977005/ https://ncbi.nlm.nih.gov/pubmed/24364358 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja4086726 |
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