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Mutationally activated Rho GTPases in cancer

The Rho family of GTPases (members of the Ras superfamily) are best known for their roles in regulating cytoskeletal dynamics. It is also well established that misregulation of Rho proteins contributes to tumorigenesis and metastasis. Unlike Ras proteins, which are frequently mutated in cancer (arou...

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Detalhes bibliográficos
Main Authors: Alan, Jamie K, Lundquist, Erik A
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3976972/
https://ncbi.nlm.nih.gov/pubmed/24088985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/sgtp.26530
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