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Sigma receptor 1 modulates ER stress and Bcl2 in murine retina

Sigma receptor 1 (σR1), a non-opiate transmembrane protein located on endoplasmic reticulum (ER) and mitochondrial membranes, is considered a molecular chaperone. Marked protection against cell death has been observed when ligands for σR1 have been used in in vitro and in vivo models of retinal cell...

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Hlavní autoři: Ha, Yonju, Shanmugam, Arul K., Markand, Shanu, Zorrilla, Eric, Ganapathy, Vadivel, Smith, Sylvia B.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3976706/
https://ncbi.nlm.nih.gov/pubmed/24469320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00441-013-1774-8
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