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Mitochondrial dysfunction in amyotrophic lateral sclerosis – a valid pharmacological target?

Amyotrophic lateral sclerosis (ALS) is an adult-onset neurodegenerative disease characterized by the selective death of upper and lower motor neurons which ultimately leads to paralysis and ultimately death. Pathological changes in ALS are closely associated with pronounced and progressive changes i...

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Podrobná bibliografie
Hlavní autoři: Muyderman, H, Chen, T
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Publishing Ltd 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3976630/
https://ncbi.nlm.nih.gov/pubmed/24148000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12476
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