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Mitochondrial dysfunction in amyotrophic lateral sclerosis – a valid pharmacological target?
Amyotrophic lateral sclerosis (ALS) is an adult-onset neurodegenerative disease characterized by the selective death of upper and lower motor neurons which ultimately leads to paralysis and ultimately death. Pathological changes in ALS are closely associated with pronounced and progressive changes i...
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| Main Authors: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Blackwell Publishing Ltd
2014
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3976630/ https://ncbi.nlm.nih.gov/pubmed/24148000 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12476 |
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