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A drug-resistant mutation in the ribosomal DNA of Tetrahymena.

A mutation that confers resistance to the drug paromomycin is shown to be in the structural gene that codes for the ribosomal RNA in Tetrahymena. This observation was made by exploiting a variant of the ribosomal DNA that distorts amplification of this locus when a new somatic nucleus develops durin...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Bruns, P J, Katzen, A L, Martin, L, Blackburn, E H
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1985
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC397662/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2986140/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.9.2844
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