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Chemoenzymatic Synthesis of ADP-D-glycero-β-D-manno-Heptose and Study of the Substrate Specificity of HldE

An efficient one-pot three enzymes strategy for chemoenzymatic synthesis of ADP-D-glycero-β-D-manno-heptose (ADP-D, D-heptose) was reported using chemically synthesized D, D-heptose-7-phosphate and the ADP-D, D-heptose biosynthetic enzymes HldE and GmhB. Moreover, the result of investigating substra...

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Autores principales: Li, Tiehai, Wen, Liuqing, Williams, Adriel, Wu, Baolin, Li, Lei, Qu, Jingyao, Meisner, Jeffrey, Xiao, Zhongying, Fang, Junqiang, Wang, Peng George
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3976583/
https://ncbi.nlm.nih.gov/pubmed/24412338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2013.12.019
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