Exenatide induces aortic vasodilation increasing hydrogen sulphide, carbon monoxide and nitric oxide production

BACKGROUND: It has been reported that GLP-1 agonist exenatide (exendin-4) decreases blood pressure. The dose-dependent vasodilator effect of exendin-4 has previously been demonstrated, although the precise mechanism is not thoroughly described. Here we have aimed to provide in vitro evidence for the...

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Bibliografiske detaljer
Main Authors: Sélley, Eszter, Kun, Szilárd, Szijártó, István András, Laczy, Boglárka, Kovács, Tibor, Fülöp, Ferenc, Wittmann, István, Molnár, Gergő A
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2014
Fag:
Original Investigation
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3976540/
https://ncbi.nlm.nih.gov/pubmed/24693878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2840-13-69
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