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Gene hunting in the genomic era: Approaches to diagnostic dilemmas in patients with primary immunodeficiencies
There are more than 180 different genetic causes of primary immunodeficiencies identified to date. Approaches for identifying causative mutations can be broadly classified into 3 strategies: (1) educated guesses based on known signaling pathways essential for immune cell development and function, (2...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2013
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3976463/ https://ncbi.nlm.nih.gov/pubmed/24100122 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2013.08.021 |
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