Inhibition of Fatty Acid Binding Proteins Elevates Brain Anandamide Levels and Produces Analgesia

The endocannabinoid anandamide (AEA) is an antinociceptive lipid that is inactivated through cellular uptake and subsequent catabolism by fatty acid amide hydrolase (FAAH). Fatty acid binding proteins (FABPs) are intracellular carriers that deliver AEA and related N-acylethanolamines (NAEs) to FAAH...

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Main Authors: Kaczocha, Martin, Rebecchi, Mario J., Ralph, Brian P., Teng, Yu-Han Gary, Berger, William T., Galbavy, William, Elmes, Matthew W., Glaser, Sherrye T., Wang, Liqun, Rizzo, Robert C., Deutsch, Dale G., Ojima, Iwao
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2014
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3976407/
https://ncbi.nlm.nih.gov/pubmed/24705380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0094200
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