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Congenital cataract, facial dysmorphism and demyelinating neuropathy (CCFDN) in 10 Czech gypsy children – frequent and underestimated cause of disability among Czech gypsies

BACKGROUND: Congenital Cataract Facial Dysmorphism and demyelinating Neuropathy (CCFDN, OMIM 604468) is an autosomal recessive multi-system disorder which was first described in Bulgarian Gypsies in 1999. It is caused by the homozygous founder mutation c.863 + 389C > T in the CTDP1 gene. The synd...

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Detalhes bibliográficos
Main Authors: Lassuthova, Petra, Šišková, Dana, Haberlová, Jana, Sakmaryová, Iva, Filouš, Aleš, Seeman, Pavel
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3976362/
https://ncbi.nlm.nih.gov/pubmed/24690360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1172-9-46
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