Pertussis toxin inhibits fMet-Leu-Phe- but not phorbol ester-stimulated changes in rabbit neutrophils: role of G proteins in excitation response coupling.

Addition of pertussis toxin to rabbit neutrophils inhibits the fMet-Leu-Phe- induced increases in Na+ influx and in intracellular pH. In addition, pretreatment of the cells with the toxin inhibits the decrease in the levels of phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 4-phosphat...

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Volpi, M, Naccache, P H, Molski, T F, Shefcyk, J, Huang, C K, Marsh, M L, Munoz, J, Becker, E L, Sha'afi, R I
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1985
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC397634/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3157993/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.9.2708
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