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Compromised paraspeckle formation as a pathogenic factor in FUSopathies
Paraspeckles are nuclear bodies formed by a set of specialized proteins assembled on the long non-coding RNA NEAT1; they have a role in nuclear retention of hyperedited transcripts and are associated with response to cellular stress. Fused in sarcoma (FUS) protein, linked to a number of neurodegener...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3976330/ https://ncbi.nlm.nih.gov/pubmed/24334610 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddt622 |
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