Minocycline and Risperidone Prevent Microglia Activation and Rescue Behavioral Deficits Induced by Neonatal Intrahippocampal Injection of Lipopolysaccharide in Rats

BACKGROUND: Various signs of activation of microglia have been reported in schizophrenia, and it is hypothesized that microglia activation is closely associated with the neuropathology of schizophrenia. METHODS: Neonatal intrahippocampal injection of lipopolysaccharide (LPS), an activator of microgl...

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Detalhes bibliográficos
Main Authors: Zhu, Furong, Zheng, Yingjun, Ding, Yu-qiang, Liu, Yong, Zhang, Xianghui, Wu, Renrong, Guo, Xiaofeng, Zhao, Jingping
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3976322/
https://ncbi.nlm.nih.gov/pubmed/24705495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0093966
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