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Initiation of transcription from each of the two human mitochondrial promoters requires unique nucleotides at the transcriptional start sites.

Promoters for transcriptional initiation on each strand of human mtDNA lie in close proximity in the displacement-loop region. Transcription initiates within these promoter elements, providing an opportunity to analyze the effects of nucleotide sequence changes on the efficiency and fidelity of this...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Hixson, J E, Clayton, D A
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1985
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC397624/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3857608/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.9.2660
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