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Benefit–risk assessment of new and emerging treatments for hepatitis C: focus on simeprevir and sofosbuvir
Greater understanding of the hepatitis C virus (HCV) genome and life cycle of the HCV virion allows for new targets for therapy that directly act on the viral machinery to inhibit replication. Numerous direct-acting antivirals are in development, and four have been brought to market. Simeprevir, a s...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Dove Medical Press
2014
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3976205/ https://ncbi.nlm.nih.gov/pubmed/24729731 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DHPS.S43304 |
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