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Variegated Expression of Hsp22 Transgenic Reporters Indicates Cell-specific Patterns of Aging in Drosophila Oenocytes

The cytoplasmic chaperone gene Hsp70 and the mitochondrial chaperone gene Hsp22 are upregulated during normal aging in Drosophila in tissue-general patterns. In addition, Hsp22 reporters are dramatically upregulated during aging in a subset of the oenocytes (liver-like cells). Hsp22 reporter express...

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Autors principals: Tower, John, Landis, Gary, Gao, Rebecca, Luan, Albert, Lee, Jonathan, Sun, Yuanyue
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3976136/
https://ncbi.nlm.nih.gov/pubmed/23723429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glt078
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