Novaferon, a novel recombinant protein produced by DNA-shuffling of IFN-α, shows antitumor effect in vitro and in vivo

OBJECTIVE: A recombinant antitumor/antiviral protein (Novaferon, Nova) is a new type of interferon, which is produced by artificial design technology combining DNA-shuffling and High Throughput Screening (HTS). METHODS: The in vitro biological activities, such as anti-tumor activity and antiviral ac...

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Autori principali: Li, Meng, Rao, Chunming, Pei, Dening, Wang, Lan, Li, Yonghong, Gao, Kai, Wang, Minrong, Wang, Junzhi
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2014
Soggetti:
Primary Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3976097/
https://ncbi.nlm.nih.gov/pubmed/24467885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2867-14-8
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