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Sequence-specific recognition of B-DNA by oligo(N-methylpyrrolecarboxamide)s.

Four homologous oligopeptide-EDTA molecules, tri-, tetra, penta-, and hexa(N-methylpyrrolecarboxamide)-EDTA, in the presence of Fe(II), O2, and dithiothreitol, cleave 32P-end-labeled restriction fragments from plasmid pBR322 DNA at common locations rich in A X T base pairs that differ in the size of...

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Bibliographic Details
Main Authors: Youngquist, R S, Dervan, P B
Format: Artigo
Language:Inglês
Published: 1985
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC397604/
https://ncbi.nlm.nih.gov/pubmed/2986122
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