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Genetic polymorphisms in warfarin and tacrolimus-related genes VKORC1, CYP2C9 and CYP3A5 in the Greek-Cypriot population

BACKGROUND: Two variants in the gene encoding the cytochrome P450 2C9 enzyme (CYP2C9) are considered the most significant genetic risk factors associated with bleeding after warfarin prescription. A variant in the vitamin K epoxide reductase (VKORC1) has been also associated by several studies with...

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Detalhes bibliográficos
Main Authors: Hadjipanagi, Despina, Chrysanthou, Stephanie, Voskarides, Konstantinos, Deltas, Constantinos
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3975864/
https://ncbi.nlm.nih.gov/pubmed/24593903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-7-123
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