Topical Application of a Mucoadhesive Freeze-Dried Black Raspberry Gel Induces Clinical and Histologic Regression and Reduces Loss of Heterozygosity Events in Premalignant Oral Intraepithelial Lesions.: Results from a Multi-Centered, Placebo Controlled Clinical Trial

PURPOSE: Approximately 30%higher-grade premalignant oral intraepithelial neoplasia (OIN) lesions will progress to oral cancer. While surgery is the OIN treatment mainstay, many OIN lesions recur which is highly problematic for both surgeons and patients. This clinical trial assessed the chemoprevent...

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Detalhes bibliográficos
Main Authors: Mallery, Susan R., Tong, Meng, Shumway, Brian S., Curran, Alice E., Larsen, Peter E., Ness, Gregory M., Kennedy, Kelly S., Blakey, George H., Kushner, George M., Vickers, Aaron M., Han, Brian, Pei, Ping, Stoner, Gary D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3975696/
https://ncbi.nlm.nih.gov/pubmed/24486592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-13-3159
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