Intravenous injection of soluble antigen induces thymic and peripheral T-cells apoptosis.

The mechanism by which tolerance is induced via systemic administration of high doses of aqueous antigen has been analyzed by using mice transgenic for a T-cell receptor specific for the influenza virus hemagglutinin (HA) peptide comprising amino acids 126-138. After intravenous injection of 750 (bu...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Liblau, R S, Tisch, R, Shokat, K, Yang, X, Dumont, N, Goodnow, C C, McDevitt, H O
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39756/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8610163/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.7.3031
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