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Nature of the charged-group effect on the stability of the C-peptide helix.

The residues responsible for the pH-dependent stability of the helix formed by the isolated C-peptide (residues 1-13 of ribonuclease A) have been identified by chemical synthesis of analogues and measurement of their helix-forming properties. Each of the residues ionizing between pH 2 and pH 8 has b...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Shoemaker, K R, Kim, P S, Brems, D N, Marqusee, S, York, E J, Chaiken, I M, Stewart, J M, Baldwin, R L
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1985
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC397555/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3857585/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.8.2349
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