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NH2-terminal arm of phage lambda repressor contributes energy and specificity to repressor binding and determines the effects of operator mutations.

Several lines of evidence indicate that the phage lambda repressor recognizes its operator by using, in part, an alpha helix (the "recognition helix"), which it inserts into the major groove of DNA. In addition to its recognition helix, lambda repressor has an "arm," consisting o...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Eliason, J L, Weiss, M A, Ptashne, M
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1985
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC397553/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3157988/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.8.2339
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