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Hypoxia differentially regulated CXCR4 and CXCR7 signaling in colon cancer
BACKGROUND: HIF-1α and CXCR4/CXCL12 have crucial roles in the metastatic process of colorectal cancer. Our aim was to study the significance of targeting HIF-1α and the CXCR4/CXCL12 axis in colorectal cancer to prevent the dissemination process in vitro. METHODS: We investigated CXCR4 and CXCR7 mRNA...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3975457/ https://ncbi.nlm.nih.gov/pubmed/24629239 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-13-58 |
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