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Identification and functional characterization of leukotriene B4 20-hydroxylase of human polymorphonuclear leukocytes.

A single reaction product was formed during the incubation of 1.5 microM (5S,12R)-dihydroxy-6,14-cis-8,10-trans-[3H]icosatetraenoic acid (leukotriene B4, LTB4) for 30 min at 37 degrees C in 10 mM potassium phosphate buffer (pH 7.5) with 100 microM NADPH and the 150,000 X g supernatant of sonicated h...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Soberman, R J, Harper, T W, Murphy, R C, Austen, K F
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1985
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC397543/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2986111/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.8.2292
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