The α2CDel322-325 adrenergic receptor polymorphism is not associated with heart failure due to idiopathic dilated cardiomyopathy in black Africans

BACKGROUND: A four-amino acid deletion was identified within the α(2C)-adrenergic receptor (α(2C)Del322-325) that, when homozygous, increases the risk of heart failure in African-Americans nearly six-fold. We hypothesised that homozygosity for the α(2C)Del322-325 polymorphism may be a risk factor fo...

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Main Authors: Du Preez, J, Matolweni, LO, Mayosi, BM, Greenberg, J, Mntla, P, Adeyemo, AA
Format: Artigo
Jezik:Inglês
Izdano: Clinics Cardive Publishing 2008
Teme:
Cardiovascular Topics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3975310/
https://ncbi.nlm.nih.gov/pubmed/18320080
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