Functional polymorphism in aldehyde dehydrogenase-2 gene associated with risk of tuberculosis

BACKGROUND: The well-known genetic polymorphisms in ADH1B(His47Arg) and ALDH2(Glu487Lys) have dramatic effects on the rate of metabolizing alcohol and acetaldehyde. We investigated possible involvement of these functional polymorphisms in other common complex-trait diseases. METHODS: The genetic eff...

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Détails bibliographiques
Auteurs principaux: Park, Seung Kyu, Park, Choon-Sik, Lee, Hyo-Suk, Park, Kyong Soo, Park, Byung Lae, Cheong, Hyun Sub, Shin, Hyoung Doo
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2014
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3975138/
https://ncbi.nlm.nih.gov/pubmed/24690209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-15-40
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