AIDing Chromatin and Transcription-Coupled Orchestration of Immunoglobulin Class-Switch Recombination

Secondary diversification of the antibody repertoire upon antigenic challenge, in the form of immunoglobulin heavy chain (IgH) class-switch recombination (CSR) endows mature, naïve B cells in peripheral lymphoid organs with a limitless ability to mount an optimal humoral immune response, thus expedi...

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Main Authors: Vaidyanathan, Bharat, Yen, Wei-Feng, Pucella, Joseph N., Chaudhuri, Jayanta
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2014
Teme:
Immunology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3975107/
https://ncbi.nlm.nih.gov/pubmed/24734031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2014.00120
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