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Bevacizumab Efficacy in Metastatic Colorectal Cancer is Dependent on Primary Tumor Resection

PURPOSE: Bevacizumab plus fluoropyrimidine-based chemotherapy is standard treatment for first-line and second-line metastatic colorectal cancer (mCRC). However, to date, there is no current biomarker predictive for the benefit of bevacizumab use for these patients. Preclinical data suggest that the...

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Bibliografiske detaljer
Main Authors: Ghiringhelli, Francois, Bichard, Damien, Limat, Samuel, Lorgis, Veronique, Vincent, Julie, Borg, Christophe, Berthou, Julie, Orry, David, Ortega-Deballon, Pablo, Lakkis, Zaher, Facy, Olivier, Heyd, Bruno, Rat, Patrick, Nerich, Virginie, Ladoire, Sylvain
Format: Artigo
Sprog:Inglês
Udgivet: Springer US 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3975091/
https://ncbi.nlm.nih.gov/pubmed/24419756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1245/s10434-013-3463-y
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