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Genome-wide consequences of deleting any single gene

Loss or duplication of chromosome segments can lead to further genomic changes associated with cancer. However, it is not known if only a select subset of genes is responsible for driving further changes. To determine if perturbation of any given gene in a genome suffices to drive subsequent genetic...

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Detalhes bibliográficos
Main Authors: Teng, Xinchen, Dayhoff-Brannigan, Margaret, Cheng, Wen-Chih, Gilbert, Catherine E., Sing, Cierra N., Diny, Nicola L., Wheelan, Sarah J., Dunham, Maitreya J., Boeke, Jef D., Pineda, Fernando J., Hardwick, J. Marie
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3975072/
https://ncbi.nlm.nih.gov/pubmed/24211263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2013.09.026
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