Cross-protective vaccine efficacy of the bivalent HPV vaccine against HPV31 is associated with humoral immune responses: Results from the Costa Rica Vaccine Trial

Background: We investigated the role of antibody responses as potential mechanism for the cross-protective vaccine-efficacies (VE) observed from randomized clinical trials of the HPV16/18 bivalent vaccine. Results: HPV31 cases had lower HPV16 antibody levels than controls (OR(4th quartile compared w...

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Main Authors: Safaeian, Mahboobeh, Kemp, Troy J., Pan, David Yuanji, Porras, Carolina, Rodriguez, Ana Cecilia, Schiffman, Mark, Cortes, Bernal, Katki, Hormuzd, Wacholder, Sholom, Schiller, John T., Gonzalez, Paula, Penrose, Kerri, Lowy, Douglas R., Quint, Wim, van Doorn, Leen-Jan, Herrero, Rolando, Hildesheim, Allan, Pinto, Ligia A.
Formato: Artigo
Idioma:Inglês
Publicado: Landes Bioscience 2013
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Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3974884/
https://ncbi.nlm.nih.gov/pubmed/23571174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/hv.24340
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