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Emerging roles of Jab1/CSN5 in DNA damage response, DNA repair, and cancer

Jab1/CSN5 is a multifunctional protein that plays an important role in integrin signaling, cell proliferation, apoptosis, and the regulation of genomic instability and DNA repair. Dysregulation of Jab1/CSN5 activity has been shown to contribute to oncogenesis by functionally inactivating several key...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Pan, Yunbao, Yang, Huiling, Claret, Francois X
Format: Artigo
Sprache:Inglês
Veröffentlicht: Landes Bioscience 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3974825/
https://ncbi.nlm.nih.gov/pubmed/24495954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.27823
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