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Proteolysis at a Specific Extracellular Residue Implicates Integral Membrane CLAG3 in Malaria Parasite Nutrient Channels

The plasmodial surface anion channel mediates uptake of nutrients and other solutes into erythrocytes infected with malaria parasites. The clag3 genes of P. falciparum determine this channel’s activity in human malaria, but how the encoded proteins contribute to transport is unknown. Here, we used p...

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Bibliografske podrobnosti
Main Authors: Nguitragool, Wang, Rayavara, Kempaiah, Desai, Sanjay A.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3974804/
https://ncbi.nlm.nih.gov/pubmed/24699906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0093759
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