Studies on Inhibition of Respiratory Cytochrome bc (1) Complex by the Fungicide Pyrimorph Suggest a Novel Inhibitory Mechanism

The respiratory chain cytochrome bc (1) complex (cyt bc (1)) is a major target of numerous antibiotics and fungicides. All cyt bc (1) inhibitors act on either the ubiquinol oxidation (Q(P)) or ubiquinone reduction (Q(N)) site. The primary cause of resistance to bc (1) inhibitors is target site mutat...

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Autores principales: Xiao, Yu-Mei, Esser, Lothar, Zhou, Fei, Li, Chang, Zhou, Yi-Hui, Yu, Chang-An, Qin, Zhao-Hai, Xia, Di
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3974799/
https://ncbi.nlm.nih.gov/pubmed/24699450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0093765
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