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Identification of Two Tyrosine Residues Required for the Intramolecular Mechanism Implicated in GIT1 Activation

GIT1 is an ArfGAP and scaffolding protein regulating cell adhesion and migration. The multidomain structure of GIT1 allows the interaction with several partners. Binding of GIT1 to some of its partners requires activation of the GIT1 polypeptide. Our previous studies indicated that binding of paxill...

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Detalhes bibliográficos
Main Authors: Totaro, Antonio, Astro, Veronica, Tonoli, Diletta, de Curtis, Ivan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3974724/
https://ncbi.nlm.nih.gov/pubmed/24699139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0093199
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