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Over-Expression of Either MECP2_e1 or MECP2_e2 in Neuronally Differentiated Cells Results in Different Patterns of Gene Expression

Mutations in MECP2 are responsible for the majority of Rett syndrome cases. MECP2 is a regulator of transcription, and has two isoforms, MECP2_e1 and MECP2_e2. There is accumulating evidence that MECP2_e1 is the etiologically relevant variant for Rett. In this study we aim to detect genes that are d...

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Detalhes bibliográficos
Main Authors: Orlic-Milacic, Marija, Kaufman, Liana, Mikhailov, Anna, Cheung, Aaron Y. L., Mahmood, Huda, Ellis, James, Gianakopoulos, Peter J., Minassian, Berge A., Vincent, John B.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3974668/
https://ncbi.nlm.nih.gov/pubmed/24699272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0091742
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