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High-Throughput Screening for the Identification of New Therapeutic Options for Metastatic Pheochromocytoma and Paraganglioma

Drug repurposing or repositioning is an important part of drug discovery that has been growing in the last few years for the development of therapeutic options in oncology. We applied this paradigm in a screening of a library of about 3,800 compounds (including FDA-approved drugs and pharmacological...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Giubellino, Alessio, Shankavaram, Uma, Bullova, Petra, Schovanek, Jan, Zhang, Yaqin, Shen, Min, Patel, Nikita, Elkahloun, Abdel, Lee, Min-Jung, Trepel, Jane, Ferrer, Marc, Pacak, Karel
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3974653/
https://ncbi.nlm.nih.gov/pubmed/24699253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0090458
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